Anti-Liver Arginase Antibody [ARG1/8869R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [ARG1/8869R] antibody to Liver Arginase.
Specificity
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Applications
WB, IHC-P
Positive Control
293T cells. Hepatocellular carcinoma (HCC) or liver.
Dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant human ARG1 protein fragment (aa1-200). The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ARG1/8869R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
35-38 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
A I, Al, ARG 1, arg1, ARGI1_HUMAN, Arginase 1, Arginase liver, Arginase type I, Arginase, liver, Arginase-1, Arginase1, Liver type arginase, Liver-type arginase, Type I arginase
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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