Recombinant Anti-Liver Arginase Antibody [ARG1/7514R] (A315253)

Anti-Liver Arginase Antibody [ARG1/7514R]

Recombinant rabbit monoclonal [ARG1/7514R] antibody to Liver Arginase.

Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Hepatocellular Carcinoma (HCC).

IHC: 1-2 µg/ml

Human

Recombinant human ARG1 protein fragment (aa300-400). The exact sequence is proprietary.

Rabbit

Monoclonal

ARG1/7514R

kappa

Protein A/G chromatography.

200 µg/ml

35-38 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.