Mouse monoclonal [PCRP-LIN28A-1E2] antibody to Lin28A.
Specificity
LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.
Applications
Flow Cytometry
Positive Control
HeLa or U87 cells.
Dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 134-187) of human LIN28A protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-LIN28A-1E2
Isotype
IgG2a
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
22.74 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
CSDD1, FLJ12457, LIN 28, Lin 28 homolog A (C. elegans), Lin-28A, LIN28, LN28A_HUMAN, Protein lin-28 homolog A, ZCCHC1, zinc finger CCHC domain containing 1, Zinc finger CCHC domain-containing protein 1
