Anti-Leishmania Lpg Antibody [CA7AE] (A279985)

Anti-Leishmania Lpg Antibody [CA7AE]

Mouse monoclonal [CA7AE] antibody to Leishmania Lpg.

This antibody recognises lipophosphoglycan (LPG) the major cell surface glycoconjugate of Leishmania parasites. recognises the repeat carbohydrate epitope of most species of Leishmania LPG. The epitope is also found on the excreted acid phosphatase of Leishmania and is expressed on the surface of Leishmania infected macrophages. recognises the promastigotes of Leishmania donovani but not those of the related species L. tropica (Jaffe and Sarfstein 1987, Sundar et al. 2001). Mouse anti Leishmania lipophosphoglycan antibody, clone CA7AE does however recognize a broad range of L. donovani and L. major strains and related species including L. infantum, L. m. mexicana, L. aethiopica and L. b. panamensis.

ELISA, IF, WB

ELISA: 1:1,000, IF: 1:500 - 1:1,000

Protozoa

Heat killed Leishmania donovani promastigotes.

Mouse

Monoclonal

CA7AE

IgM

Unconjugated

Ascitic Fluid.

Lyophilized

Reconstitute with 0.5 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Supplied without preservatives.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C.

Mouse anti Leishmania lipophosphoglycan antibody, clone CA7AE recognizes lipophosphoglycan (LPG) the major cell surface glycoconjugate of Leishmania parasites. Mouse anti Leishmania lipophosphoglycan antibody, clone CA7AE recognizes the repeat carbohydrate epitope of most species of Leishmania LPG. The epitope is also found on the excreted acid phosphatase of Leishmania and is expressed on the surface of Leishmania infected macrophages (Tolson et al. 1990). Mouse anti Leishmania lipophosphoglycan antibody, clone CA7AE recognizes the promastigotes of Leishmania donovani but not those of the related species L. tropica (Jaffe and Sarfstein 1987, Sundar et al. 2001). Mouse anti Leishmania lipophosphoglycan antibody, clone CA7AE does however recognize a broad range of L. donovani and L. major strains and related species including L. infantum, L. m. mexicana, L. aethiopica and L. b. panamensis (Tolson et al. 1994).