Anti-Langerin Antibody [LGRN/7357] - BSA and Azide free (A316623)

$765

Mouse monoclonal [LGRN/7357] antibody to Langerin for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Langerin Antibody [LGRN/7357] - BSA and Azide free
Description
Mouse monoclonal [LGRN/7357] antibody to Langerin.
Specificity
Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
Applications
IHC-P
Positive Control
Human skin.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 50-250) of human Langerin protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
LGRN/7357
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
48 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
C type lectin domain family 4 member K, C-type lectin domain family 4 member K, CD 207, CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, CLC4K_HUMAN, CLEC 4K, CLEC4K, Langerhans cell specific c type lectin, RGD1565913
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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