Anti-Ku70 Antibody [KU729] (A248673)

Anti-Ku70 Antibody [KU729]

Mouse monoclonal [KU729] antibody to Ku70.

This antibody recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Flow Cytometry, IF, ICC

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, ICC: 1-2 µg/ml

Human

This antibody is predicted to cross react with Mouse, Rat, or Chicken.

Nuclear extract of human HL-60 cells.

Mouse

Monoclonal

KU729

IgG1

kappa

Unconjugated

200 µg/ml

70 kDa / 80 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Ku70 Antibody [KU729] - BSA and Azide free (A251855).

5''-deoxyribose-5-phosphate lyase Ku70, 5''-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, G22P1, Ku 70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, Ku p70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Kup70, Lupus Ku autoantigen protein p70, ML8, Thyroid autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid-lupus autoantigen, TLAA, X ray repair complementing defective repair in Chinese hamster cells 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X-ray repair cross-complementing protein 6, XRCC 6, Xrcc6, XRCC6_HUMAN