Recombinant Anti-Ki67 Antibody [MKI67/4947R] (A278028)

Anti-Ki67 Antibody [MKI67/4947R]

Recombinant rabbit monoclonal [MKI67/4947R] antibody to Ki67.

Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 2,293-2,478, of human Ki67 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

MKI67/4947R

IgG

Protein A/G chromatography.

200 µg/ml

345 kDa / 395 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Ki67 Antibody [MKI67/4947R] - BSA and Azide free (A278616).

Antigen identified by monoclonal, Antigen KI-67, Antigen KI67, KI67_HUMAN, KIA, Marker of proliferation Ki-67, MIB, MIB 1, MKI67, PPP1R105, Proliferation marker protein Ki-67, Proliferation related Ki 67 antigen, Protein phosphatase 1 regulatory subunit 105, RP11-380J17.2