Anti-Von Willebrand Factor Anticorpo [VWF/2480] (A253498)

Anti-Von Willebrand Factor Antibody [VWF/2480] - BSA and Azide free

Mouse monoclonal [VWF/2480] antibody to Von Willebrand Factor.

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

IHC-P

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human VWF protein.

Mouse

Monoclonal

VWF/2480

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

250 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Von Willebrand Factor Antibody [VWF/2480] (A250318).

Coagulation factor VIII , Coagulation factor VIII VWF, F8VWF, Factor VIII related antigen, von Willebrand antigen 2, von Willebrand antigen II, Von Willebrand disease, VWD, vWF, VWF_HUMAN