Ricombinante Anti-Von Willebrand Factor Anticorpo [rVWF/1465] (A250328)

Anti-Von Willebrand Factor Antibody [rVWF/1465]

Recombinant mouse monoclonal [rVWF/1465] antibody to Von Willebrand Factor.

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

WB, IP, IHC-P

WB: 1-2 µg/ml, IP: 0.5-1 µg / 500 µg protein lysate, IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 1815-1939, of human vWF protein. The exact sequence is proprietary.

Mouse

Monoclonal

rVWF/1465

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

250 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Von Willebrand Factor Antibody [rVWF/1465] - BSA and Azide free (A253508).

Coagulation factor VIII , Coagulation factor VIII VWF, F8VWF, Factor VIII related antigen, von Willebrand antigen 2, von Willebrand antigen II, Von Willebrand disease, VWD, vWF, VWF_HUMAN