Ricombinante Anti-Tyrosinase Anticorpo [rOCA1/812] (A253423)

Anticorpo monoclonale [rOCA1/812] di topo contro Tyrosinase per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Tyrosinase Antibody [rOCA1/812] - BSA and Azide free
Descrizione
Recombinant mouse monoclonal [rOCA1/812] antibody to Tyrosinase.
Specificità
This antibody recognizes a cluster of proteins between 70-80kDa, identified as tyrosinase. Occasionally a minor band at 55kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants.This MAb is a useful marker for melanocytes and melanomas.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human Tyrosinase protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
rOCA1/812
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
70-80 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Tyrosinase Antibody [rOCA1/812] (A250243).
Sinonimi
ATN, CMM8, LB24 AB, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, OCAIA, Oculocutaneous albinism IA, SHEP3, SK29 AB, SK29-AB, Tumor rejection antigen AB, TYR, tyrosinase (oculocutaneous albinism IA), TYRO_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-Tyrosinase Anticorpo [rOCA1/812] (A253423)

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