Ricombinante Anti-Topoisomerase II alpha Anticorpo [rTOP2A/8339] (A315742)

Anti-Topoisomerase II alpha Antibody [rTOP2A/8339]

Recombinant mouse monoclonal [rTOP2A/8339] antibody to Topoisomerase II alpha.

It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.

IHC-P

HeLa or Jurkat cells. Human lymph node or tonsil.

IHC: 0.5-1 µg/ml

Human

Recombinant human Topoisomerase II alpha fragment (aa1300-1500). The exact sequence is proprietary.

Mouse

Monoclonal

rTOP2A/8339

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

170 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

alpha isozyme, ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing), DNA topoisomerase 2 alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA Topoisomerase2, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, Topoisomerase DNA II alpha 170kDa, TP2A