Ricombinante Anti-TOP1MT Anticorpo [rTOP1MT/488] (A278468)

Name: Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free
Brand: Antibodies.com
SKU: A278468
Price: 525.0 USD
Availability: InStock

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$525

Anticorpo monoclonale [rTOP1MT/488] di topo contro TOP1MT per Flow Cytometry, IF, WB e IHC-P.

Garanzia al 100%

Garanzia di corrispondenza del prezzo

Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Consegna

Spese di spedizione

$40

Tempi di consegna

4-6 Giorni lavorativi

Contattaci

Telefono

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanzie

Garanzia di qualità al 100%

Garanzia di corrispondenza del prezzo

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Anticorpo Ricombinante

Descrizione Prodotto

Nome

Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free

Descrizione

Recombinant mouse monoclonal [rTOP1MT/488] antibody to TOP1MT.

Specificità

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Applicazioni

Flow Cytometry, IF, WB, IHC-P

Diluizioni consigliate

Flow Cytometry: 0.5-1 µg/million cells, IF: 0.5-1 µg/ml, WB: 0.5-2 µg/ml, IHC-P: 1-2 µg/ml

Reattività

Human

Immunogeno

Recombinant full-length human TOP1MT protein.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

rTOP1MT/488

Isotipo

IgG1

Catene leggere

kappa

Coniugare

Unconjugated

Purificazione

Protein A/G chromatography.

Concentrazione

1 mg/ml

Peso molecolare

70 kDa

Forma del prodotto

Liquid

Formulazione

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Conservazione

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Note generali

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-TOP1MT Antibody [rTOP1MT/488] (A277880).

Sinonimi

2900052H09Rik, DNA topoisomerase I, DNA topoisomerase I, mitochondrial, mitochondrial, TOP1M_HUMAN, Topoisomerase I mitochondrial

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Immagini (2)

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Figure 1: Immunohistochemistry - Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free (A278468)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver tissue using Anti-TOP1MT Antibody [rTOP1MT/488].

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Figure 2: SDS-PAGE - Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free (A278468)

SDS-PAGE analysis of Anti-TOP1MT Antibody [rTOP1MT/488] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.