Anti-TLR4 Anticorpo [TLR4/230] (A250152)

Anticorpo monoclonale [TLR4/230] di topo contro TLR4 per Functional Studies.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-TLR4 Antibody [TLR4/230]
Descrizione
Mouse monoclonal [TLR4/230] antibody to TLR4.
Specificità
This antibody reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Applicazioni
Functional Studies
Reattività
Human, Monkey, Porcine, Canine, Rat, Guinea Pig
Immunogeno
Recombinant full-length human TLR4 protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
TLR4/230
Isotipo
IgG2a
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
95-120 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TLR4 Antibody [TLR4/230] - BSA and Azide free (A253332).
Sinonimi
ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4_HUMAN, TOLL, Toll like receptor 4, Toll-like receptor 4
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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