Ricombinante Anti-TL1A Anticorpo [VEGI/7799R] (A315734)

$765

Anticorpo monoclonale [VEGI/7799R] di coniglio contro TL1A per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-TL1A Antibody [VEGI/7799R]
Descrizione
Recombinant rabbit monoclonal [VEGI/7799R] antibody to TL1A.
Specificità
VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.
Applicazioni
IHC-P
Controllo positivo
Endothelial cells. Colon, intestine, placenta, lung or prostate.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human VEGI protein.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
VEGI/7799R
Isotipo
IgG
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A chromatography.
Concentrazione
200 µg/ml
Peso molecolare
22 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
MGC129934, MGC129935, tl1, TL1 A, tnf ligand related molecule 1, TNF ligand-related molecule 1, tnf superfamily ligand tl1a, TNF15_HUMAN, TNFSF15, Tumor necrosis factor (ligand) superfamily member 15, Tumor necrosis factor ligand superfamily member 15, Tumor necrosis factor ligand superfamily member 15, secreted form, Vascular endothelial cell growth inhibitor, Vascular endothelial growth inhibitor, Vascular endothelial growth inhibitor 192a, vegi, VEGI192A
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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