Anti-Thyroglobulin Anticorpo [SPM517] (A250106)

Anticorpo monoclonale [SPM517] di topo contro Thyroglobulin per Flow Cytometry e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Thyroglobulin Antibody [SPM517]
Descrizione
Mouse monoclonal [SPM517] antibody to Thyroglobulin.
Specificità
Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Applicazioni
Flow Cytometry, IHC-P
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml
Reattività
Human, Mouse, Rat
Immunogeno
Human thyroid follicular cells.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
SPM517
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
660 kDa (dimeric Form)
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Thyroglobulin Antibody [SPM517] - BSA and Azide free (A253286).
Sinonimi
AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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