Mouse monoclonal [TGFA/1119] antibody to TGF alpha.
Specificità
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Applicazioni
IHC-P
Diluizioni consigliate
IHC-P: 2-4 µg/ml
Reattività
Human
Immunogeno
Recombinant full-length human TGF alpha protein.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
TGFA/1119
Isotipo
IgG1
Catene leggere
kappa
Coniugare
Unconjugated
Purificazione
Protein A/G chromatography.
Concentrazione
200 µg/ml
Peso molecolare
~6 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.