Anti-Tenascin C Anticorpo [TNC/4806] (A315716)

Anti-Tenascin C Antibody [TNC/4806]

Mouse monoclonal [TNC/4806] antibody to Tenascin C.

In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

IHC-P

Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell, and lung carcinomas. Staining of normal fibroblasts serves as internal positive control (IHC).

IHC: 2-4 µg/ml

Human

Recombinant human full-length TNC protein.

Mouse

Monoclonal

TNC/4806

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

210 kDa / 300 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

150 225, Cytotactin, Glioma associated extracellular matrix antigen, Glioma-associated-extracellular matrix antigen, GMEM, GP, GP 150 225, GP 150-225, Hexabrachion, HXB, JI, MGC167029, Miotendinous antigen, Myotendinous antigen, Neuronectin, Tenascin, Tenascin-C, Tenascin-C isoform 14/AD1/16, TenascinC, TENA_HUMAN, TN, TN C, TN-C, TNC