Anti-TAP1 Anticorpo (A283077)

Anti-TAP1 Antibody

Rabbit polyclonal antibody to TAP1.

This antibody recognises an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an ~81 kDa membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex.TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells.Rabbit anti Human TAP1 antibody (AHP1248) does not cross react with human TAP2.

WB, ELISA, Flow Cytometry, IP

ELISA: 1:10,000, WB: 1:1,000

Human

TAP1 peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Haemocyanin.

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml

Approximately 72 kDa

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human TAP1 antibody detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an ~81 kDa membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex. TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells.Rabbit anti Human TAP1 antibody ( AHP1248) does not cross react with human TAP2.

ABC 17, ABC transporter MHC 1, ABC17, ABCB 2, ABCB2, Antigen peptide transporter 1, APT 1, APT1, ATP binding cassette sub family B (MDR/TAP) member 2, ATP binding cassette sub family B member 2, ATP binding cassette transporter, ATP-binding cassette sub-family B member 2, D6S114E, FLJ26666, FLJ41500, Peptide supply factor 1, Peptide transporter involved in antigen processing 1, Peptide transporter PSF 1, Peptide transporter PSF1, Peptide transporter TAP 1, Peptide transporter TAP1, PSF 1, PSF-1, PSF1, Really interesting new gene 4 protein, RING 4, RING4, TAP 1, TAP1*0102N, TAP1N, TAP1_HUMAN, Transporter 1 ATP binding cassette sub family B, Transporter 1 ATP binding cassette sub family B (MDR/TAP), Transporter associated with antigen processing, Transporter ATP binding cassette major histocompatibility complex 1, Y3