Ricombinante Anti-Synaptophysin Anticorpo [SYP/7976R] (A315705)

Anti-Synaptophysin Antibody [SYP/7976R]

Recombinant rabbit monoclonal [SYP/7976R] antibody to Synaptophysin.

This recombinant rabbit monoclonal antibody recognizes a protein of 38kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

IHC-P

HepG2, HeLa or Y79 cells. Human pancreas, cerebellum or pheochromocytoma.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 274-313) of human Synaptophysin (SYP) protein. The exact sequence is proprietary.

Rabbit

Monoclonal

SYP/7976R

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

38 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Syp, SYPH, SYPH_HUMAN, SypI