Ricombinante Anti-Stathmin 1 Anticorpo [STMN1/8001R] (A315679)

Anti-Stathmin 1 Antibody [STMN1/8001R]

Recombinant rabbit monoclonal [STMN1/8001R] antibody to Stathmin 1.

Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

IHC-P

Human brain or melanoma tissue.

IHC: 1-2 µg/ml

Human

Recombinant fragment of human STMN1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

STMN1/8001R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

19 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

C1orf215, Lag, LAP 18, LAP18, Leukemia associated phosphoprotein p18, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, OP 18, Op18, p18, p19, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, PR22, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin, Stathmin1, STMN 1, Stmn1, STMN1_HUMAN