Anti-StAR Anticorpo [STAR/3976] (A317058)

$765

Anticorpo monoclonale [STAR/3976] di topo contro StAR per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-StAR Antibody [STAR/3976] - BSA and Azide free
Descrizione
Mouse monoclonal [STAR/3976] antibody to StAR.
Specificità
Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Applicazioni
IHC-P
Controllo positivo
K-562 cells. Human adrenal or testicular carcinoma.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 39-108) of human STAR protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
STAR/3976
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
30 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
Cholesterol trafficker, Luteinizing hormone induced protein, mitochondrial, Mitochondrial steroid acute regulatory protein, StAR related lipid transfer (START) domain containing 1, StARD1, START domain containing 1, START domain containing protein 1, START domain-containing protein 1, STAR_HUMAN, Steroid acute regulatory protein, Steroidogenic acute regulator, Steroidogenic acute regulatory protein, Steroidogenic acute regulatory protein mitochondrial
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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