Anti-StAR Antibody [STAR/2077] - BSA and Azide free (A253238)

Anti-StAR Antibody [STAR/2077] - BSA and Azide free

Mouse monoclonal [STAR/2077] antibody to StAR.

Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 39-108, of human STAR protein. The exact sequence is proprietary.

Mouse

Monoclonal

STAR/2077

IgG2b

kappa

Protein A/G chromatography.

1 mg/ml

30 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-StAR Antibody [STAR/2077] (A250058).

StARD1, START domain-containing protein 1, Steroidogenic acute regulatory protein, mitochondrial