This antibody recognises secretory leukocyte protease inhibitor (SLPI), a ~14 kDa non-glycosylated protein produced by secretory cells in the respiratory, genital and lachrymal glands, and by macrophages, B-cells and neutrophils.The functions of SLPI are diverse. The SLPI protein inhibits protease activity at sites of inflammation, protecting tissues against protease mediated damage and it possesses anti-microbial/anti-viral activity. In addition, SLPI has been reported to exhibit anti-inflammatory properties, regulating lipopolysaccharide induced activation of NF-kappa beta in peripheral blood monocytes.

Applicazioni

WB, IHC-P

Diluizioni consigliate

WB: 1.0 - 2 µg/ml

Reattività

Human, Mouse

Immunogeno

A peptide corresponding to 17 amino acids near the centre of human SLPI.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

1 mg/ml

Peso molecolare

Approximately 14 kDa in Daudi cell lysates.

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Conservazione

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Note generali

Rabbit anti Human SLPI antibody recognizes secretory leukocyte protease inhibitor (SLPI), a ~14 kDa non-glycosylated protein produced by secretory cells in the respiratory, genital and lachrymal glands, and by macrophages, B-cells and neutrophils. The functions of SLPI are diverse. The SLPI protein inhibits protease activity at sites of inflammation, protecting tissues against protease mediated damage and it possesses anti-microbial/anti-viral activity. In addition, SLPI has been reported to exhibit anti-inflammatory properties, regulating lipopolysaccharide induced activation of NF-kappa beta in peripheral blood monocytes.

Sinonimi

ALK 1, ALK1, ALP, Antileukoprotease, Antileukoproteinase, Antileukoproteinase 1, Antileukoproteinase1, BLPI, Human seminal protease inhibitor, HUSI, HUSI 1, HUSI I, HUSI-1, MPI, Mucus proteinase inhibitor, Protease inhibitor WAP4, Secretory leukocyte peptidase inhibitor, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, SLPI_HUMAN, WAP four disulfide core domain protein 4, WAP four-disulfide core domain protein 4, WAP4, WFDC4

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.