Anti-Siglec 7 Anticorpo [S7.7] (FITC) (A281724)

$420

Anticorpo monoclonale [S7.7] di topo contro Siglec 7 (FITC) per Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-Siglec 7 Antibody [S7.7] (FITC)
Descrizione
Mouse monoclonal [S7.7] antibody to Siglec 7 (FITC).
Specificità
This antibody recognises human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classed as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Mouse anti Human Siglec-7 antibody, cloneS7.7 is a blocking antibody , and has been shown to recognize Siglec-7 in Rhesus monkey.
Applicazioni
Flow Cytometry
Diluizioni consigliate
Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells.
Reattività
Human, Rhesus Monkey
Immunogeno
Siglec-7 3T3 transfected cells.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
S7.7
Isotipo
IgG1
Coniugare

FITC

Excitation: 490nm, Emission: 525nm

Purificazione
Protein G affinity chromatography of tissue culture supernatant.
Concentrazione
100 µg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Note generali
Mouse anti Human Siglec-7 antibody, cloneS7.7 recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classed as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Mouse anti Human Siglec-7 antibody, cloneS7.7 is a blocking antibody (Avril et al. 2006), and has been shown to recognize Siglec-7 in Rhesus monkey (Jaroenpool et al. 2007).
Sinonimi
Adhesion inhibitory receptor molecule 1, Adhesion inhibitory receptor molecule 1, siglec 7, AIRM 1, AIRM-1, AIRM1, CD328, CD328 antigen, CDw328, D siglec, D-siglec, HLDA 8, p75, p75/AIRM1, QA79, QA79 membrane protein, Sialic acid binding Ig like lectin 7, Sialic acid binding immunoglobulin like lectin 7, Sialic acid-binding Ig-like lectin 7, SIGL7_HUMAN, Siglec-7, SIGLEC19P, SIGLEC7, SIGLECP2
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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