Anti-SHP1 Anticorpo [PTPN6/7544] (A317022)

$765

Anticorpo monoclonale [PTPN6/7544] di topo contro SHP1 per IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-SHP1 Antibody [PTPN6/7544] - BSA and Azide free
Descrizione
Mouse monoclonal [PTPN6/7544] antibody to SHP1.
Specificità
PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle/marginal zone lymphomas (SHP-1+) from follicular lymphomas (SHP-1 negative).
Applicazioni
IHC-P
Controllo positivo
Human tonsil, lymph node or spleen.
Diluizioni consigliate
IHC: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment (around Amino Acids 395-595) of human PTPN6 protein. The exact sequence is proprietary.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
PTPN6/7544
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
65 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sinonimi
70Z-SHP, EC 3.1.3.48, HCP, HCPH, Hematopoietic cell phosphatase, Hematopoietic cell protein tyrosine phosphatase, Hematopoietic cell protein-tyrosine phosphatase, HPTP1C, Protein tyrosine phosphatase 1C, Protein tyrosine phosphatase non receptor type 6, Protein tyrosine phosphatase SHP1, Protein-tyrosine phosphatase 1C, protein-tyrosine phosphatase SHP 1, Protein-tyrosine phosphatase SHP-1, PTN6_HUMAN, PTP 1C, PTP-1C, PTP1C, Ptpn6, SH PTP 1, SH PTP1, SH-PTP1, SHP 1, SHP 1L, SHP1L, tyrosine protein phosphatase non receptor type 6, Tyrosine-protein phosphatase non-receptor type 6
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

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