Anti-S100P Anticorpo [S100P/7373] (A315598)

Anti-S100P Antibody [S100P/7373]

Mouse monoclonal [S100P/7373] antibody to S100P.

S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

WB, IHC-P

Human pancreatic adenocarcinoma, placenta or spleen tissue. SK-BR3 cells.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-95) of human MIG9 protein. The exact sequence is proprietary.

Mouse

Monoclonal

S100P/7373

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

10 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

MIG9, Migration inducing gene 9, Protein S100-E, Protein S100-P, Protein S100P, S100 calcium binding protein P, S100 calcium-binding protein P, S100 P, S100E, S100P_HUMAN