Anti-RNA Polymerase II CTD repeat YSPTSPS Anticorpo [CTD4H8] (A252834)

Anticorpo monoclonale [CTD4H8] di topo contro RNA Polymerase II CTD repeat YSPTSPS per Flow Cytometry, IF, WB e IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Spese di spedizione
Tempi di consegna
4-6 Giorni lavorativi
Telefono
+1 (314) 370-6046
Lun - Ven, 8:00 - 16:00 AST
E-mail
orders@antibodies.com
Nome
Anti-RNA Polymerase II CTD repeat YSPTSPS Antibody [CTD4H8] - BSA and Azide free
Descrizione
Mouse monoclonal [CTD4H8] antibody to RNA Polymerase II CTD repeat YSPTSPS.
Specificità
RNA polymerase II (Pol II) is an enzyme that is composed of 12 subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis and subsequent transcription elongation cannot occur.
Applicazioni
Flow Cytometry, IF, WB, IHC-P
Diluizioni consigliate
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human, Mouse, Rat
Immunogeno
Ten repeats of synthetic peptide YSPTSPS using chemically synthesized phospho Ser5.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
CTD4H8
Isotipo
IgG1
Catene leggere
kappa
Coniugare

Unconjugated

Purificazione
Protein A/G chromatography.
Concentrazione
1 mg/ml
Peso molecolare
192-253 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Note generali
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-RNA Polymerase II CTD repeat YSPTSPS Antibody [CTD4H8] (A249654).
Sinonimi
DNA directed RNA polymerase II A, DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, hRPB220, hsRPB1, POLR2, Polr2a, POLRA, Polymerase (RNA) II (DNA directed) polypeptide A, Polymerase (RNA) II (DNA directed) polypeptide A 220kDa, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RPB1, RPB1_HUMAN, RPBh1, RpIILS, RPO2, RPOL2
Dichiarazione di non responsabilità
Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Prodotti alternativi a Anti-RNA Polymerase II CTD repeat YSPTSPS Anticorpo [CTD4H8] (A252834)

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