Anti-RIP2 Anticorpo (A283150)

Anti-RIP2 Antibody

Rabbit polyclonal antibody to RIP2.

This antibody recognises human Receptor-interacting serine/threonine-protein kinase 2, also known as RIP2, RIPK2, RIP-like-interacting CLARP kinase or CARD-containing interleukin-1 beta-converting enzyme-associated kinase. RIP2 is a 403 amino acid ~60 kDa cytoplasmic protein belonging to the protein kinase superfamily. RIP2 is a kinase that regulates TNF and Fas induced-apoptosis and is involved in the generation of the pro-inflammatory cytokine IL-1beta. Over expression of RIP2 has been shown to induce apoptosis, and the activation of NF-Kappa-B and JNK. RIP2 is widely expressed in a range of human tissues.

WB, IHC-Fr

IHC-Fr: 10 µg/ml, WB: 0.5 - 1 µg/ml

Human, Rat, Mouse

A peptide corresponding to amino acids near the N-terminus of human RIP2.

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml

Approximately 60 kDa in A431 cell lysates.

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human RIP2 antibody recognizes Human Receptor-interacting serine/threonine-protein kinase 2, also known as RIP2, RIPK2, RIP-like-interacting CLARP kinase or CARD-containing interleukin-1 beta-converting enzyme-associated kinase. RIP2 is a 403 amino acid ~60 kDa cytoplasmic protein belonging to the protein kinase superfamily. RIP2 is a kinase that regulates TNF and Fas induced-apoptosis and is involved in the generation of the pro-inflammatory cytokine IL-1beta. Over expression of RIP2 has been shown to induce apoptosis, and the activation of NF-Kappa-B and JNK. RIP2 is widely expressed in a range of human tissues.

CARD 3, CARD carrying kinase, CARD containing ICE associated kinase, CARD containing IL 1 beta ICE kinase, CARD containing IL1 beta ICE kinase, CARD containing interleukin 1 beta converting enzyme (ICE) associated kinase, CARD containing interleukin 1 beta converting enzyme associated kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARD3, CARDIAK, CCK, CLARP kinase, GIG 30, GIG30, Growth inhibiting gene 30, Receptor interacting protein (RIP) like interacting caspase like apoptosis regulatory protein (CLARP) kinase, Receptor interacting protein 2, Receptor interacting serine threonine kinase 2, Receptor interacting serine/threonine protein kinase 2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2, RICK, RIP 2, RIP like interacting CLARP kinase, RIP-2, RIP-like-interacting CLARP kinase, RIPK 2, Ripk2, RIPK2_HUMAN, TNFRSF, Tyrosine-protein kinase RIPK2, UNQ277/PRO314/PRO34092