This antibody recognises rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR). RICTOR and mTORC2 have been shown to play an essential role in embryonic growth and development, perhaps due to the control that mTORC2 exerts on actin cytoskeleton organization.

Applicazioni

Diluizioni consigliate

WB: 0.5 - 4.0 µg/ml

Reattività

Mouse, Human, Rat

Immunogeno

Synthetic peptide corresponding to residues surrounding amino acid 1639 of mouse RICTOR.

Specie ospite

Rabbit

Clonalità

Polyclonal

Isotipo

IgG

Coniugare

Unconjugated

Concentrazione

500 µg/ml

Peso molecolare

Approximately 190 kDa in HeLa and Jurkat lysates.

Forma del prodotto

Liquid

Formulazione

Supplied in Phosphate Buffered Saline with 30% Glycerol, 0.5% BSA, and 0.03% ProClin 300.

Conservazione

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Note generali

Rabbit anti RICTOR antibody recognizes rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR).RICTOR and mTORC2 have been shown to play an essential role in embryonic growth and development, perhaps due to the control that mTORC2 exerts onactincytoskeleton organization.

Sinonimi

AVO3, AVO3 homolog, DKFZp686B11164, hAVO3, KIAA1999, Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae), mAVO3, MGC39830, PIA, Pianissimo, Rapamycin insensitive companion of mTOR, Rapamycin-insensitive companion of mTOR, RICTR, RICTR_HUMAN, RPTOR independent companion of MTOR complex 2, TORC2 specific protein AVO3

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Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.