Anti-RBP4 Anticorpo [RB42] (A281650)

Anti-RBP4 Antibody [RB42]

Mouse monoclonal [RB42] antibody to RBP4.

This antibody recognises human serum Retinol Binding Protein 4 (RBP4), a single-chain glycoprotein belonging to the lipocalin family, which is responsible for the transport of Retinol (vitamin A1) from the liver to peripheral target tissues. In plasma, the RBP4-retinol complex interacts with transthyretin preventing its loss through filtration through the kidney glomeruli. Defects in RBP4 are a cause of retinol-binding protein deficiency and can cause night vision problems. RBP4 has been described as an adipokine that contributes to insulin resistance in mice. recognises free RBP4 and RBP4 in complex with transthyretin. It reacts with apo- as well as holo-RBP4. It recognises human RBP4 in western blotting under reducing conditions.

WB, ELISA

Human

Human recombinant Retinol Binding Protein 4.

Mouse

Monoclonal

RB42

IgG1

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Retinol Binding Protein 4 antibody, clone RB42 recognizes human serum Retinol Binding Protein 4 (RBP4), a single-chain glycoprotein belonging to the lipocalin family, which is responsible for the transport of Retinol (vitamin A1) from the liver to peripheral target tissues. In plasma, the RBP4-retinol complex interacts with transthyretin preventing its loss through filtration through the kidney glomeruli. Defects in RBP4 are a cause of retinol-binding protein deficiency and can cause night vision problems. RBP4 has been described as an adipokine that contributes to insulin resistance in mice. Mouse anti Human Retinol Binding Protein 4 antibody, clone RB42 recognizes free RBP4 and RBP4 in complex with transthyretin. It reacts with apo- as well as holo-RBP4. It recognizes human RBP4 in western blotting under reducing conditions.

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