Anti-PTEN Anticorpo [PTEN/7345] (A315537)

Anti-PTEN Antibody [PTEN/7345]

Mouse monoclonal [PTEN/7345] antibody to PTEN.

PTEN (phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase) contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. It was identified as a tumor suppressor that is mutated in a large number of cancers, including sporadic brain, breast, kidney, and prostate cancers.

ELISA, IHC-P

MCF-7 or HeLa cells. Human prostate, breast, liver or renal carcinoma.

IHC: 1-2 µg/ml

Human

Recombinant full-length human PTEN protein.

Mouse

Monoclonal

PTEN/7345

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

10q23del, BZS, DEC, GLM2, MGC11227, MHAM, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, Phosphatase and tensin like protein, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, PTEN1, PTEN_HUMAN, TEP1