Ricombinante Anti-Prostate Specific Antigen Anticorpo [rKLK3/6947] (A315533)

Anti-Prostate Specific Antigen Antibody [rKLK3/6947]

Recombinant mouse monoclonal [rKLK3/6947] antibody to Prostate Specific Antigen.

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests.

IHC-P

PC12 cells. Normal prostate or prostate carcinoma tissues.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 150-250) of human KLK3 (PSA) protein. The exact sequence is proprietary.

Mouse

Monoclonal

rKLK3/6947

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

33-34 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

antigen, prostate-specific, APS, Gamma seminoprotein, Gamma-seminoprotein, hK3, Kallikrein 3, Kallikrein related peptidase 3, Kallikrein-3, KLK 3, KLK2A1, Klk3, KLK3_HUMAN, P-30 antigen, P30 antigen, Prostate-specific antigen, Psa, Semenogelase, Seminin