Transglutaminase 2 è un gene codificato dal simbolo TGM2. È noto anche come: Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); Transglutaminase H; TGase H; Transglutaminase-2; TGase-2; TGM2. Transglutaminase 2 ha una massa di 77.33kDa e una lunghezza di amminoacidi di 687.
Offriamo 3 proteine Transglutaminase 2
Informazioni su geni e proteine
Riepilogo UniProt
Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins.
Sommario di Entrez
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Somiglianze di sequenza
Belongs to the transglutaminase superfamily. Transglutaminase family.
