Neurotrophin 3 è un gene codificato dal simbolo NTF3. Comunemente indicato anche come: Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor; NTF3. Neurotrophin 3 ha una massa di 29.36kDa e una lunghezza di amminoacidi di 257.
Offriamo 2 proteine Neurotrophin 3
Informazioni su geni e proteine
Riepilogo UniProt
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Sommario di Entrez
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Specificità del tessuto
Brain and peripheral tissues.
Somiglianze di sequenza
Belongs to the NGF-beta family.
Posizione cellulare
Secreted.
