Neuritin è un gene codificato dal simbolo NRN1. Comunemente indicato anche come: NRN1; NRN. Neuritin ha una massa di 15.33kDa e una lunghezza di amminoacidi di 142.
Offriamo 2 proteine Neuritin
Informazioni su geni e proteine
Riepilogo UniProt
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
Sommario di Entrez
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.
Somiglianze di sequenza
Belongs to the neuritin family.
Posizione cellulare
Cell membrane. Cell junction > Synapse.
