LFA3 è un gene codificato dal simbolo CD58. Comunemente indicato anche come: Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58. LFA3 ha una massa di 28.15kDa e una lunghezza di amminoacidi di 250.
Offriamo 3 proteine LFA3
Informazioni su geni e proteine
Riepilogo UniProt
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Sommario di Entrez
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
Posizione cellulare
Cell membrane.
