GM-CSF è un gene codificato dal simbolo CSF2. Comunemente indicato anche come: Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF. GM-CSF ha una massa di 16.3kDa e una lunghezza di amminoacidi di 144.
Offriamo 15 proteine GM-CSF
Informazioni su geni e proteine
Riepilogo UniProt
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Sommario di Entrez
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
Somiglianze di sequenza
Belongs to the GM-CSF family.
Posizione cellulare
Secreted.
