CD34 è un gene codificato dal simbolo CD34. È noto anche come Hematopoietic progenitor cell antigen CD34. CD34 ha una massa di 40.72kDa e una lunghezza di amminoacidi di 385.
Offriamo 5 proteine CD34
Informazioni su geni e proteine
Riepilogo UniProt
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Sommario di Entrez
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.
Specificità del tessuto
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Somiglianze di sequenza
Belongs to the CD34 family.
Modifica post-translazionale
Highly glycosylated.
Posizione cellulare
Membrane.
