CD2 è un gene codificato dal simbolo CD2. Altri nomi includono: T-cell surface antigen Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; SRBC. CD2 ha una massa di 39.45kDa e una lunghezza di amminoacidi di 351.
Offriamo 7 proteine CD2
Informazioni su geni e proteine
Riepilogo UniProt
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Sommario di Entrez
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene.
Posizione cellulare
Cell membrane.
