BCA1 è un gene codificato dal simbolo CXCL13. Altri nomi includono: C-X-C motif chemokine 13; Angie; B cell-attracting chemokine 1; BCA-1; B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13; CXCL13; BLC; SCYB13. BCA1 ha una massa di 12.66kDa e una lunghezza di amminoacidi di 109.
Offriamo 4 proteine BCA1
Informazioni su geni e proteine
Riepilogo UniProt
Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.
Sommario di Entrez
B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.
Specificità del tessuto
Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen.
Somiglianze di sequenza
Belongs to the intercrine alpha (chemokine CxC) family.
Posizione cellulare
Secreted.
