ZDHHC9 è un gene codificato dal simbolo ZDHHC9. È noto anche come: Palmitoyltransferase Zinc finger DHHC domain-containing protein 9; DHHC-9; Zinc finger protein 379; Zinc finger protein 380; CXorf11; ZDHHC10; ZNF379; ZNF380. ZDHHC9 ha una massa di 40.92kDa, una lunghezza di amminoacidi di 364, ed è implicato in Mental retardation, X-linked, syndromic, ZDHHC9-related.
Offriamo 8 anticorpi contro ZDHHC9, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.
Sommario di Entrez
This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.
Specificità del tessuto
Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.
Coinvolgimento nella malattia
Mental retardation, X-linked, syndromic, ZDHHC9-related: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Some MRXSZ patients have marfanoid habitus as an additional feature.
Somiglianze di sequenza
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Posizione cellulare
Endoplasmic reticulum membrane. Golgi apparatus membrane.
