Vitronectin è un gene codificato dal simbolo VTN. È noto anche come: VN; S-protein; Serum-spreading factor; V75; VTN. Vitronectin ha una massa di 54.31kDa e una lunghezza di amminoacidi di 478.
Offriamo 7 anticorpi contro Vitronectin, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Sommario di Entrez
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Specificità del tessuto
Expressed in the retina pigment epithelium (at protein level) (PubMed:25136834). Plasma.
Modifica post-translazionale
Sulfated on tyrosine residues.
Posizione cellulare
Secreted > Extracellular space.
