VAV2 è un gene codificato dal simbolo VAV2. È noto anche come Guanine nucleotide exchange factor VAV-2. VAV2 ha una massa di 101.29kDa e una lunghezza di amminoacidi di 878.
Offriamo 8 anticorpi contro VAV2, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).
Sommario di Entrez
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specificità del tessuto
Widely expressed.
Modifica post-translazionale
Phosphorylated on tyrosine residues in response to FGR activation.
