USF1 è un gene codificato dal simbolo USF1. È noto anche come: Upstream stimulatory factor 1; Class B basic helix-loop-helix protein 11; bHLHb11; Major late transcription factor 1; BHLHB11; USF. USF1 ha una massa di 33.54kDa, una lunghezza di amminoacidi di 310, ed è implicato in Hyperlipidemia, familial combined, 1.
Offriamo 6 anticorpi contro USF1, allevati nel Coniglio, che sono adatti per WB, IHC, ICC/IF e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Sommario di Entrez
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.
Coinvolgimento nella malattia
Hyperlipidemia, familial combined, 1: A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease.
Posizione cellulare
Nucleus.
