TSC22D1 è un gene codificato dal simbolo TSC22D1. È noto anche come: TSC22 domain family protein 1; Cerebral protein 2; Regulatory protein TSC-22; TGFB-stimulated clone 22 homolog; Transforming growth factor beta-1-induced transcript 4 protein; KIAA1994; TGFB1I4; TSC22. TSC22D1 ha una massa di 109.68kDa e una lunghezza di amminoacidi di 1073.
Offriamo 7 anticorpi contro TSC22D1, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter.
Sommario di Entrez
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specificità del tessuto
Widely expressed in fetal and adult tissues.
Somiglianze di sequenza
Belongs to the TSC-22/Dip/Bun family.
Posizione cellulare
Cytoplasm. Nucleus.
