Anticorpi TMPRSS3

6 prodotti

TMPRSS3 è un gene codificato dal simbolo TMPRSS3. È noto anche come: Transmembrane protease serine 3; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein; ECHOS1; TADG12. TMPRSS3 ha una massa di 49.41kDa, una lunghezza di amminoacidi di 454, ed è implicato in Deafness, autosomal recessive, 8.

Offriamo 6 anticorpi contro TMPRSS3, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati ​​da Umano, Topo e Ratto.

Informazioni su geni e proteine

Riepilogo UniProt
Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).
Sommario di Entrez
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Specificità del tessuto
Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
Coinvolgimento nella malattia
Deafness, autosomal recessive, 8: A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Somiglianze di sequenza
Belongs to the peptidase S1 family.
Modifica post-translazionale
Undergoes autoproteolytic activation.
Posizione cellulare
Endoplasmic reticulum membrane.
Western Blot - Anti-TMPRSS3 Antibody (C10761) - Antibodies.com
(3)
Visualizza prodotto10µg Dimensione di prova
Western Blot - Anti-TMPRSS3 Antibody (R12-3633) - Antibodies.com
Visualizza prodotto10µg Dimensione di prova
Western Blot - Anti-TMPRSS3 Antibody (A83475) - Antibodies.com
Anti-TMPRSS3 (F440) Antibody from Bioworld Technology (BS2289) - Antibodies.com
(2)
Western blot - TMPRSS3 Antibody from Signalway Antibody (33829) - Antibodies.com
(2)
Immunohistochemistry - TMPRSS3 Antibody from Signalway Antibody (43162) - Antibodies.com

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