TIMP4 è un gene codificato dal simbolo TIMP4. È noto anche come: Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4. TIMP4 ha una massa di 25.5kDa e una lunghezza di amminoacidi di 224.
Offriamo 7 anticorpi contro TIMP4, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Sommario di Entrez
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Specificità del tessuto
Abundant in heart and present at low levels in many other tissues.
Somiglianze di sequenza
Belongs to the protease inhibitor I35 (TIMP) family.
Posizione cellulare
Secreted.
