TIM 1 è un gene codificato dal simbolo HAVCR1. È noto anche come: Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; T-cell membrane protein 1; HAVCR1; KIM1; TIM1; TIMD1. TIM 1 ha una massa di 39.25kDa e una lunghezza di amminoacidi di 364.
Offriamo 10 anticorpi contro TIM 1, allevati nel Coniglio, Capra e Ratto, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair.
Sommario di Entrez
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19.
Specificità del tessuto
Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
Somiglianze di sequenza
Belongs to the immunoglobulin superfamily. TIM family.
Posizione cellulare
Membrane.
