TGF beta Receptor III è un gene codificato dal simbolo TGFBR3. È noto anche come: Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III; TGFBR3. TGF beta Receptor III ha una massa di 93.5kDa e una lunghezza di amminoacidi di 851.
Offriamo 6 anticorpi contro TGF beta Receptor III, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Sommario di Entrez
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Modifica post-translazionale
Extensively modified by glycosaminoglycan groups (GAG).
Posizione cellulare
Secreted. Secreted > Extracellular space. Cell membrane.
Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
