Synaptotagmin è un gene codificato dal simbolo SYT5. È noto anche come: Synaptotagmin-5 V; SytV; SYT5. Synaptotagmin ha una massa di 42.9kDa e una lunghezza di amminoacidi di 386.
Offriamo 10 anticorpi contro Synaptotagmin, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity).
Sommario di Entrez
This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants.
Somiglianze di sequenza
Belongs to the synaptotagmin family.
Posizione cellulare
Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Recycling endosome membrane.
In mast cells, localizes to the endocytic recycling compartment.
